Description

(3S,αr)-3-[[(E)-HydroxyiminoAcetyl]Amino]-α-(4-Hydroxyphenyl)-2-Oxo-1-Azetidineacetic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex β-lactam (azetidinone) core structure. This compound is of significant commercial interest for its role as a key synthetic precursor in the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of specialized antibiotics and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel β-lactam antibiotics and other pharmacologically active compounds.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new drug candidates targeting bacterial infections.
• Chemical Synthesis: Serves as a versatile chiral synthon for constructing complex molecular architectures in organic and process chemistry.
• Biochemical Research: Potential use as a tool compound in enzymatic studies, particularly those involving β-lactamases or penicillin-binding proteins.

Basic Information

Product Name	(3S,αr)-3-[[(E)-HydroxyiminoAcetyl]Amino]-α-(4-Hydroxyphenyl)-2-Oxo-1-Azetidineacetic Acid
CAS No.	63598-46-9
Molecular Formula	C19H17N3O6
Molecular Weight	383.36 g/mol
Synonyms	(3S,trans)-3-[[(E)-(Hydroxyimino)(4-hydroxyphenyl)acetyl]amino]-4-(4-hydroxyphenyl)-2-azetidinone-1-acetic acid; (3S,αr)-3-[[(E)-HydroxyiminoAcetyl]Amino]-α-(4-Hydroxyphenyl)-2-Oxo-1-Azetidineacetic Acid; Azetidinone derivative, 63598-46-9; β-Lactam intermediate with hydroxyphenyl groups; 1-Azetidineacetic acid derivative; (3S,trans)-3-[[(Z)-(Hydroxyimino)(4-hydroxyphenyl)acetyl]amino]-4-(4-hydroxyphenyl)-2-azetidinone-1-acetic acid (isomer)
EINECS	Contact for details

Quality Control

Our (3S,αr)-3-[[(E)-HydroxyiminoAcetyl]Amino]-α-(4-Hydroxyphenyl)-2-Oxo-1-Azetidineacetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available upon request to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.