Description

(3S,αr)-3-[[(Z)-HydroxyiminoAcetyl]Amino]-α-(4-Hydroxyphenyl)-2-Oxo-1-Azetidineacetic Acid is a high-purity, non-natural β-lactam derivative of significant interest in advanced pharmaceutical research and development. Its complex molecular architecture, featuring a hydroxyphenyl-substituted azetidinone core, makes it a critical intermediate for synthesizing novel bioactive compounds. This product is essential for R&D chemists and process development scientists in the pharmaceutical and fine chemical industries, particularly those focused on antibiotic research, enzyme inhibition studies, and the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel β-lactam antibiotics and other specialized active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving β-lactamases or penicillin-binding proteins.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new drug candidates with improved efficacy and safety profiles.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex target molecules.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(3S,αr)-3-[[(Z)-HydroxyiminoAcetyl]Amino]-α-(4-Hydroxyphenyl)-2-Oxo-1-Azetidineacetic Acid
CAS No.	63555-59-9
Molecular Formula	C24H21N3O7
Molecular Weight	463.44 g/mol
Synonyms	(3S,4R)-3-[[(Z)-Hydroxyiminoacetyl]amino]-4-(4-hydroxyphenyl)-2-oxo-1-azetidineacetic acid; (3S,4R)-3-[[(Z)-(4-Hydroxybenzoyl)hydroxyimino]amino]-4-(4-hydroxyphenyl)-2-oxoazetidine-1-acetic acid; 3-[[(Z)-HydroxyiminoAcetyl]Amino]-α-(4-Hydroxyphenyl)-2-Oxo-1-Azetidineacetic Acid; 1-Azetidineacetic acid, 3-[[(Z)-hydroxyiminoacetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-, (3S,4R)-; β-lactam derivative 63555-59-9.
EINECS	Contact for details

Quality Control

Our (3S,αr)-3-[[(Z)-HydroxyiminoAcetyl]Amino]-α-(4-Hydroxyphenyl)-2-Oxo-1-Azetidineacetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates for regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.