Description

2-Amino-6-(4-Methyl-1-Piperazinyl)Benzonitrile is a specialized aromatic nitrile derivative featuring a substituted piperazine moiety, serving as a crucial advanced intermediate in modern synthetic chemistry. Its molecular architecture makes it a valuable building block for constructing complex pharmacologically active molecules, particularly in the development of kinase inhibitors and other targeted therapeutics. This high-purity compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical synthesis specialists seeking to innovate in drug discovery and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Organic Synthesis Building Block: Utilized in heterocyclic and medicinal chemistry for constructing complex molecular scaffolds due to its reactive amino and nitrile functional groups.
• Research & Development: Serves as a critical reagent in academic and industrial R&D for exploring new chemical entities and reaction methodologies.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value specialty chemicals and advanced materials.
• Agrochemical Intermediate: Potential use in the development of new active ingredients for crop protection products.

Basic Information

Product Name	2-Amino-6-(4-Methyl-1-Piperazinyl)Benzonitrile
CAS No.	63365-17-3
Molecular Formula	C₁₂H₁₅N₅
Molecular Weight	229.28 g/mol
Synonyms	2-Amino-6-(4-methylpiperazin-1-yl)benzonitrile; 6-(4-Methyl-1-piperazinyl)-2-aminobenzonitrile; 2-Amino-6-(4-methyl-1-piperazinyl)benzonitrile; Benzonitrile, 2-amino-6-(4-methyl-1-piperazinyl)-; 63365-17-3; 2-Amino-6-(4-methylpiperazin-1-yl)phenyl cyanide
EINECS	Contact for details

Quality Control

Our 2-Amino-6-(4-Methyl-1-Piperazinyl)Benzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.