Description

(6Ar)-6Aα,12Aα-Dihydro-4-Methoxy-2-(3-Methyl-2-Butenyl)-6H-[1,3]Dioxolo[5,6]Benzofuro[3,2-C][1]Benzopyran-3-Ol CAS NO 63343-95-3 is a complex, naturally-derived benzofurobenzopyran compound, often associated with the kavalactone class of phytochemicals. This compound is of significant interest for its potential as a high-purity reference standard and as a key intermediate in advanced organic synthesis. It is primarily sought by pharmaceutical research, nutraceutical development, and analytical chemistry laboratories for method development and quality control.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of related active pharmaceutical ingredients (APIs) and botanical extracts.
• Nutraceutical Research: Serves as a key analytical standard in the research and quality assurance of kava (Piper methysticum) extracts and related herbal supplements.
• Organic Synthesis Intermediate: Acts as a sophisticated building block for the synthesis of novel analogs and derivatives for biological activity screening.
• Analytical Method Development: Critical for developing and validating HPLC, UPLC, and GC-MS methods in compliance with ICH and pharmacopeial guidelines.
• Academic & Biomedical Research: Utilized in pharmacological studies to investigate structure-activity relationships and metabolic pathways.

Basic Information

Product Name	(6Ar)-6Aα,12Aα-Dihydro-4-Methoxy-2-(3-Methyl-2-Butenyl)-6H-[1,3]Dioxolo[5,6]Benzofuro[3,2-C][1]Benzopyran-3-Ol
CAS No.	63343-95-3
Molecular Formula	C23H24O6
Molecular Weight	396.44 g/mol
Synonyms	Dihydrokavain; 5,6-Dihydrokavain; DHK; 7,8-Dihydrokavain; (±)-Dihydrokavain; Dihydrokawain; 2H-1-Benzopyran-3-ol, 6a,12a-dihydro-4-methoxy-2-(3-methyl-2-butenyl)-6H-[1,3]dioxolo[5,6]benzofuro[3,2-c]-; (6aR,12aS)-6a,12a-Dihydro-4-methoxy-2-(3-methylbut-2-en-1-yl)-6H-[1,3]dioxolo[5,6]benzofuro[3,2-c]chromen-3-ol
EINECS	Contact for details

Quality Control

Our (6Ar)-6Aα,12Aα-Dihydro-4-Methoxy-2-(3-Methyl-2-Butenyl)-6H-[1,3]Dioxolo[5,6]Benzofuro[3,2-C][1]Benzopyran-3-Ol is produced and controlled under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC purity assay, chiral purity determination, and identity confirmation against an authenticated reference standard. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes batch-specific results, analytical methods, and chromatograms. Our quality commitment aligns with the standards expected for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (by chiral HPLC)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.