Description

(3A,5A,7B,12A)-3,7,12-Trihydroxy-Cholan-24-Oic Acid CAS NO 63324-19-6 is a high-purity bile acid derivative, a critical intermediate in the synthesis of pharmaceutical compounds. Its defined stereochemistry and functional groups make it an essential building block for producing therapeutic agents targeting liver and metabolic functions. This compound is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of novel drugs and diagnostic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of ursodeoxycholic acid (UDCA) and other therapeutic bile acids used to treat cholestatic liver diseases and gallstones.
• Biochemical Research: Used as a standard or reagent in studies of bile acid metabolism, hepatocyte function, and membrane transport mechanisms.
• Reference Standard: Serves as a high-purity analytical standard in HPLC and LC-MS methods for quality control and pharmacokinetic studies in pharmaceutical development.
• Fine Chemical Synthesis: Employed as a chiral starting material or intermediate for the production of more complex steroid-based molecules and drug candidates.
• Cell Culture & Diagnostics: Utilized in specialized cell culture media and diagnostic kit formulations for liver function studies.

Basic Information

Product Name	(3A,5A,7B,12A)-3,7,12-Trihydroxy-Cholan-24-Oic Acid
CAS No.	63324-19-6
Molecular Formula	C24H40O5
Molecular Weight	408.57 g/mol
Synonyms	3α,7α,12α-Trihydroxy-5β-cholan-24-oic Acid; Cholic Acid Impurity C; 3α,7α,12α-Trihydroxy-5β-cholanoic Acid; 7α,12α-Dihydroxy-3-oxo-5β-cholan-24-oic Acid (related); Hyocholic Acid (isomer); Trihydroxycholanic Acid; 5β-Cholan-24-oic Acid-3α,7α,12α-triol
EINECS	Contact for details

Quality Control

Our (3A,5A,7B,12A)-3,7,12-Trihydroxy-Cholan-24-Oic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.