Description

2-Chloro-6-Hydrazinopyrazine is a versatile and high-value heterocyclic building block, specifically a pyrazine derivative functionalized with both chloro and hydrazino groups. This bifunctional structure makes it a critical intermediate for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry, particularly for the development of novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, including kinase inhibitors, antiviral agents, and other biologically active heterocycles.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Ligand and Chelating Agent Precursor: The hydrazino group can be further modified to create complexing agents or ligands for catalysis and material science.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and cyclization reactions to construct more elaborate nitrogen-containing heterocyclic systems.
• Research & Development: Serves as a standard reagent in academic and industrial laboratories for method development and exploring new chemical spaces.
• Material Science: Potential use in the synthesis of organic semiconductors, dyes, or polymers due to its conjugated pyrazine core.

Basic Information

Product Name	2-Chloro-6-Hydrazinopyrazine
CAS No.	63286-29-3
Molecular Formula	C4H5ClN4
Molecular Weight	144.56 g/mol
Synonyms	6-Chloro-2-Hydrazinopyrazine; 2-Chloro-6-Hydrazino-1,4-Diazine; 2-Chloropyrazin-6-ylhydrazine; 2-Chloro-6-Hydrazinylpyrazine; 2-Chloro-6-Hydrazino-pyrazine; 6-Chloro-2-Hydrazinylpyrazine; (6-Chloropyrazin-2-yl)hydrazine
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Hydrazinopyrazine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white or light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 98.0% / ≥ 99.0% (High Purity Grades Available)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.