Description

2,5-Piperazinedione,1,3,4-Trimethyl-,(S)-(9Ci) is a chiral, substituted diketopiperazine derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated chiral building block and a key scaffold for the development of novel pharmaceutical intermediates and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of complex heterocyclic compounds, peptidomimetics, and potential therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Peptidomimetic Scaffold: Used to construct constrained peptide analogs and mimetics, enhancing metabolic stability and bioavailability in drug design.
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective synthesis to introduce specific stereocenters into complex molecular architectures.
• Chemical Biology Research: Serves as a probe or building block in studying protein-protein interactions and enzyme inhibition mechanisms.
• Agrochemical Development: Potential intermediate in the synthesis of novel, chiral agrochemicals with specific biological activity.
• Academic & Industrial R&D: Fundamental research material in universities and corporate labs for methodological development in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2,5-Piperazinedione,1,3,4-Trimethyl-,(S)-(9Ci)
CAS No.	63273-60-9
Molecular Formula	C7H12N2O2
Molecular Weight	156.18 g/mol
Synonyms	(S)-1,3,4-Trimethyl-2,5-piperazinedione; (S)-1,3,4-Trimethylpiperazine-2,5-dione; (S)-1,3,4-Trimethyl-2,5-diketopiperazine; (S)-TMPD; (S)-1,3,4-Trimethyl-DKP; (S)-1,3,4-Trimethyl-2,5-dioxopiperazine; (S)-1,3,4-Trimethyl-2,5-piperazinedione (9CI); (S)-1,3,4-Trimethyl-2,5-piperazinedione (9CI)
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione,1,3,4-Trimethyl-,(S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.