Description

1-Phenyl-Cyclopropanecarbonyl Chloride is a versatile and highly reactive organic intermediate, specifically an acyl chloride derivative. Its value lies in its role as a key building block for introducing the 1-phenylcyclopropyl moiety into more complex molecular architectures, a structure of significant interest in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the metabolic stability conferred by the cyclopropyl group.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the phenylcyclopropyl structure can enhance biological activity and environmental profile.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Ligand and Catalyst Preparation: Employed to create novel ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to synthesize activity-based probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for fine chemical manufacturers offering bespoke synthesis services to clients in life sciences.

Basic Information

Product Name	1-Phenyl-Cyclopropanecarbonyl Chloride
CAS No.	63201-02-5
Molecular Formula	C10H9ClO
Molecular Weight	180.63 g/mol
Synonyms	1-Phenylcyclopropanecarbonyl chloride; 1-Phenylcyclopropanecarboxylic acid chloride; Cyclopropanecarbonyl chloride, 1-phenyl-; 1-Phenylcyclopropylcarbonyl chloride; (1-Phenylcyclopropyl)carbonyl chloride; α-Phenylcyclopropanecarbonyl chloride; 1-Phenyl-1-cyclopropanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 1-Phenyl-Cyclopropanecarbonyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP manufacturing principles for applications requiring the highest quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.