Description

2,5-Dimethoxyphenylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, widely used in organic synthesis. Its core value lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon bonds, enabling the construction of complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing substituted aromatic and heterocyclic scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific dimethoxyphenyl motifs.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the creation of organic electronic materials, such as hole-transport layers or monomers for conductive polymers.
• Fine Chemical Production: Facilitates the introduction of the 2,5-dimethoxyphenyl group into dyes, fragrances, and other specialty chemicals.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in synthetic organic chemistry and exploring new reaction pathways.

Basic Information

Item	Details
Product Name	2,5-Dimethoxyphenylmagnesium Bromide
CAS No.	62890-98-6
Molecular Formula	C8H9BrMgO2
Molecular Weight	241.36 g/mol
Synonyms	(2,5-Dimethoxyphenyl)magnesium Bromide; Magnesium, Bromo(2,5-dimethoxyphenyl)-; 2,5-Dimethoxyphenylmagnesium Bromide solution; Grignard Reagent (2,5-Dimethoxyphenyl)MgBr; 1-Bromo-2,5-dimethoxybenzene magnesium derivative; 2,5-Dimethoxybenzene, bromomagnesio-; (2,5-Dimethoxybenzene)magnesium Bromide
EINECS	Contact for details

Quality Control

Our 2,5-Dimethoxyphenylmagnesium Bromide is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, concentration (typically supplied as a solution in THF or diethyl ether), and other critical parameters. We adhere to cGMP principles where applicable, and our quality systems support compliance with global regulatory requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly reactive and moisture-sensitive nature, this product must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions. The storage area must be dry, well-ventilated, and away from sources of ignition, acids, and oxidizing agents. Always use proper handling techniques to prevent exposure to air and moisture.

Specification

Item	Specification
Appearance	Clear, colorless to light brown solution
Identification (IR)	Conforms to structure
Assay (Titration)	0.5 M to 1.0 M in specified solvent (e.g., THF)
Purity (GC/HPLC)	≥ 95% (on an anhydrous basis)
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.