Description

Zidometacin is a non-steroidal anti-inflammatory drug (NSAID) belonging to the indole acetic acid class, known for its potent pharmacological activity. This compound is a key intermediate in the synthesis of advanced pharmaceutical formulations targeting inflammation and pain. It is essential for research institutions, pharmaceutical R&D laboratories, and manufacturers developing new therapeutic agents. Zidometacin CAS NO 62851-43-8 is valued for its specific structural properties that enable targeted drug development.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of novel NSAID and analgesic drug candidates.
• Biochemical Research: Used in in-vitro and in-vivo studies to investigate cyclooxygenase (COX) inhibition pathways and inflammatory mediators.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical testing laboratories.
• Preclinical Development: Employed in the formulation and efficacy testing of new anti-inflammatory medications during early-stage development.
• Academic Research: Utilized by universities and research institutes for pharmacological studies and educational purposes in medicinal chemistry.

Basic Information

Product Name	Zidometacin
CAS No.	62851-43-8
Molecular Formula	C15H13ClN2O4
Molecular Weight	320.73 g/mol
Synonyms	1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid; Zidometacine; Indometacin analog; CL-756; AF-283; Zidometacinum; 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid
EINECS	Contact for details

Quality Control

Our Zidometacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and stringent control of residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.