Description

2,5-Piperazinedione,1,3-Dimethyl-,(S)-(9Ci) is a high-purity, optically active diketopiperazine derivative. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the creation of complex molecular architectures. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), peptide mimetics, and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and oncology targets.
• Peptidomimetic Scaffold: Used to construct constrained peptide analogs and macrocyclic compounds with enhanced metabolic stability and bioavailability.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in stereoselective synthesis to introduce specific chiral centers.
• Chemical Research: Serves as a model compound in methodological studies for ring-forming reactions and heterocyclic chemistry.
• Ligand and Catalyst Development: Potential use in the design of chiral ligands for asymmetric catalysis.

Basic Information

Product Name	2,5-Piperazinedione,1,3-Dimethyl-,(S)-(9Ci)
CAS No.	62246-37-1
Molecular Formula	C6H10N2O2
Molecular Weight	142.16 g/mol
Synonyms	(S)-1,3-Dimethyl-2,5-piperazinedione; (S)-1,3-Dimethylpiperazine-2,5-dione; (S)-1,3-Dimethyldiketopiperazine; (S)-DMDKP; (S)-1,3-Dimethyl-2,5-diketopiperazine; (S)-1,3-Dimethyl-2,5-dioxopiperazine; (S)-1,3-Dimethylpiperazine-2,5-diketone
EINECS	Contact for details

Quality Control

Our production of 2,5-Piperazinedione,1,3-Dimethyl-,(S)-(9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing full specification results is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.