Description

1,1,1-Trichloro-3-(Pyrazin-2-Yl)Propan-2-Ol is a specialized halogenated organic compound featuring a pyrazine heterocycle, serving as a crucial synthetic intermediate in advanced chemical synthesis. Its unique molecular architecture, combining a trichloromethyl group with a pyrazinyl alcohol moiety, makes it a valuable building block for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry research for developing compounds with potential therapeutic activity.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides, leveraging the pyrazine ring's bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in organic synthesis for creating libraries of complex molecules for screening and structure-activity relationship (SAR) studies.
• Ligand and Catalyst Development: The heterocyclic nitrogen atoms can act as coordination sites, making it useful in the preparation of specialized ligands for catalytic systems.
• Material Science Precursor: Potential use in the synthesis of functionalized organic materials and metal-organic frameworks (MOFs) due to its reactive handles.

Basic Information

Product Name	1,1,1-Trichloro-3-(Pyrazin-2-Yl)Propan-2-Ol
CAS No.	62124-85-0
Molecular Formula	C7H5Cl3N2O
Molecular Weight	245.49 g/mol
Synonyms	2-Propanol, 1,1,1-trichloro-3-(2-pyrazinyl)-; 1,1,1-Trichloro-3-(2-pyrazinyl)-2-propanol; 3-(Pyrazin-2-yl)-1,1,1-trichloropropan-2-ol; 2-Pyrazinemethanol, α-(trichloromethyl)-; α-(Trichloromethyl)-2-pyrazinemethanol
EINECS	Contact for details

Quality Control

Our 1,1,1-Trichloro-3-(Pyrazin-2-Yl)Propan-2-Ol is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and agrochemical R&D partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.