Description

(3Ar)-3Aα,4,4Aα,5,6,8,9,9A,10,10Aα-Decahydro-9Aβ-Acetoxymethyl-8β-Hydroxy-3,5-Bis(Methylene)-6β,9β-Epoxyfuro[2,3-H][3]Benzoxepin-2(3H)-One is a complex, high-purity organic compound belonging to the class of furobenzoxepin derivatives. This specialized chemical serves as a critical advanced intermediate or reference standard in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and for analytical method development.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug molecules, particularly in oncology and anti-inflammatory research.
• Reference Standard: Used for analytical method validation, quality control, and impurity profiling in pharmaceutical manufacturing to ensure batch consistency.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new chemical entities and optimize biological activity.
• Process Chemistry Development: Serves as a model compound for developing and scaling up efficient synthetic routes under GMP-like conditions.
• Academic Research: Utilized in university and institutional labs for studying complex organic reactions and natural product synthesis.
• Custom Synthesis Starting Material: Provides a sophisticated core structure for contract research organizations (CROs) and CDMOs to develop proprietary compounds for clients.

Basic Information

Item	Detail
Product Name	(3Ar)-3Aα,4,4Aα,5,6,8,9,9A,10,10Aα-Decahydro-9Aβ-Acetoxymethyl-8β-Hydroxy-3,5-Bis(Methylene)-6β,9β-Epoxyfuro[2,3-H][3]Benzoxepin-2(3H)-One
CAS No.	61701-92-6
Molecular Formula	C20H24O7
Molecular Weight	376.40 g/mol
Synonyms	9-Acetoxy-14,15-dinorlabd-8(17)-en-13-one; 8β-Hydroxy-9α-acetoxy-13,14-dinorlabd-8(17)-en-12-one; Furo[2,3-h][3]benzoxepin derivative; Labdane diterpenoid derivative; 9α-Acetoxy-8β-hydroxy-13,14-dinorlabd-8(17)-en-12-one; (3aR,4S,6aR,8R,9S,9aR,9bS)-9-(Acetyloxy)-8-hydroxy-3,6,9-trimethyl-2-oxo-2,3,3a,4,5,6,6a,8,9,9a,9b,10-dodecahydro-4,9a-epoxybenzo[h][1]benzoxepin-7-carbaldehyde (alternative IUPAC); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of (3Ar)-3Aα,4,4Aα,5,6,8,9,9A,10,10Aα-Decahydro-9Aβ-Acetoxymethyl-8β-Hydroxy-3,5-Bis(Methylene)-6β,9β-Epoxyfuro[2,3-H][3]Benzoxepin-2(3H)-One is manufactured and controlled under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced techniques like HPLC, GC, and NMR. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and process development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.