Description

2-Chloro-6-(Methylthio)Pyrazine is a versatile heterocyclic building block characterized by its reactive chloro and methylthio substituents. This compound matters as a key synthetic intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by research chemists and process development teams for applications in medicinal chemistry, crop protection, and the synthesis of advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing antimicrobial properties.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its pyrazine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Flavor and Fragrance Chemistry: Employed in the research and synthesis of complex aroma compounds, as pyrazine derivatives are known for their nutty, roasted notes.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of organic electronic materials and polymers.
• Custom Synthesis and Contract Manufacturing: A valuable scaffold for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Chloro-6-(Methylthio)Pyrazine
CAS No.	61655-74-1
Molecular Formula	C5H5ClN2S
Molecular Weight	160.62 g/mol
Synonyms	2-Chloro-6-methylsulfanylpyrazine; 6-Chloro-2-(methylthio)pyrazine; 2-Chloro-6-methylmercaptopyrazine; 2-Chloro-6-(methylthio)-1,4-diazine; Pyrazine, 2-chloro-6-(methylthio)-; 2-Methylthio-6-chloropyrazine
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(Methylthio)Pyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.