Description

2-Chloro-6-(1-Piperazinyl)Pyrazine Monohydrochloride is a high-purity pharmaceutical intermediate and building block of significant synthetic utility. Its value lies in its role as a key precursor for the development of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic chemistry. This compound is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and fine chemical sectors seeking reliable, high-quality raw materials for complex synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• API Synthesis: Used in the multi-step production of Active Pharmaceutical Ingredients (APIs) that incorporate the piperazinylpyrazine pharmacophore.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and insecticides with specific biological activity.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening and lead optimization.
• Fine Chemical Synthesis: A versatile reagent for constructing complex heterocyclic compounds in custom synthesis and process development.

Basic Information

Product Name	2-Chloro-6-(1-Piperazinyl)Pyrazine Monohydrochloride
CAS No.	61655-58-1
Molecular Formula	C8H12ClN4•HCl
Molecular Weight	245.57 g/mol
Synonyms	2-Chloro-6-piperazin-1-ylpyrazine hydrochloride; 2-Chloro-6-(piperazin-1-yl)pyrazine hydrochloride; 6-Chloro-3-piperazin-1-ylpyrazine hydrochloride; 2-Chloro-6-(1-piperazinyl)pyrazine HCl; Piperazine, 1-(6-chloro-2-pyrazinyl)-, monohydrochloride; 1-(6-Chloro-2-pyrazinyl)piperazine hydrochloride; 2-Chloro-6-piperazinylpyrazine monohydrochloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(1-Piperazinyl)Pyrazine Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.