Description

1,2-Dipalmitoleoyl-Sn-Glycero-3-Phosphoethanolamine is a high-purity synthetic phospholipid, specifically a phosphatidylethanolamine (PE) with defined fatty acid chains. This compound is critical for researchers and formulators requiring precise lipid composition to mimic or manipulate biological membrane structure and function. It is essential for advanced applications in liposome and nanoparticle drug delivery systems, membrane biophysics research, and the development of lipid-based biochemical assays.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural phospholipid for creating stable, fusogenic vesicles for mRNA, siRNA, and small molecule drug delivery.
• Membrane Biophysics & Model Membranes: Used to construct defined lipid bilayers (e.g., supported lipid bilayers, vesicles) for studying membrane protein interactions, fluidity, and phase behavior.
• Cell Culture & Transfection Reagents: A component in complex lipid mixtures designed to enhance cellular uptake of nucleic acids and other macromolecules.
• Biochemical Research: Serves as a substrate or standard in enzymatic assays (e.g., for phospholipases) and in studies of lipid metabolism and signaling pathways.
• Cosmetic & Dermal Formulations: Incorporated into advanced cosmetic products for its biomimetic and skin-barrier repair properties.
• Diagnostic Reagents: Used in the development of diagnostic kits and sensors that utilize lipid membrane platforms.

Basic Information

Product Name	1,2-Dipalmitoleoyl-Sn-Glycero-3-Phosphoethanolamine
CAS No.	61599-23-3
Molecular Formula	C39H74NO8P
Molecular Weight	716.0 g/mol
Synonyms	PE(16:1/16:1); 1,2-Di-(cis-9-hexadecenoyl)-sn-glycero-3-phosphoethanolamine; Dipalmitoleoylphosphatidylethanolamine; DPPE (ambiguous, verify chain specificity); (2R)-2,3-Bis[[(9Z)-hexadec-9-enoyl]oxy]propyl 2-aminoethyl hydrogen phosphate; Phosphatidylethanolamine (16:1/16:1); 1,2-Dipalmitoleoylphosphatidylethanolamine; sn-Glycero-3-phosphoethanolamine-N-(dipalmitoleoyl)
EINECS	Contact for details

Quality Control

Our 1,2-Dipalmitoleoyl-Sn-Glycero-3-Phosphoethanolamine is manufactured under strict quality systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with key parameters including assay by HPLC, fatty acid profile confirmation, and limits for critical impurities. Our quality commitment supports applications in GMP-grade pharmaceutical development and high-impact research.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Store away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (IR & NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Fatty Acid Composition (GC)	≥ 95% Palmitoleic acid (C16:1)
Water Content (KF)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines
Peroxide Value	≤ 5.0 mEq/kg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.