Description

1,2-Dieicosanoyl-Sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid belonging to the phosphatidylcholine class, specifically featuring two eicosanoic (arachidic) acid chains. This compound is a critical component for constructing highly stable, long-chain lipid bilayers in advanced biomimetic membrane research and formulation development. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material science sectors who require precise, well-defined lipid structures for applications such as liposomal drug delivery systems, membrane protein studies, and model membrane platforms.

Application

• Liposomal Drug Delivery Systems: As a primary structural lipid for creating stable, long-circulating liposomes for targeted therapeutic delivery.
• Biomimetic Membrane Models: For constructing supported lipid bilayers (SLBs) and giant unilamellar vesicles (GUVs) to study membrane biophysics and protein-lipid interactions.
• Excipient in Formulations: Used in the development of lipid-based nanoparticle formulations to enhance drug solubility and bioavailability.
• Cell Membrane Research: As a defined component to investigate the effects of specific saturated long-chain phospholipids on membrane fluidity, phase behavior, and raft formation.
• Diagnostic Reagents: In the formulation of lipid components for diagnostic assays and imaging contrast agents.
• Cosmetic & Dermal Applications: As a high-quality emollient and skin-identical lipid in premium cosmetic formulations for barrier repair and moisturization.

Basic Information

Product Name	1,2-Dieicosanoyl-Sn-Glycero-3-Phosphocholine
CAS No.	61596-53-0
Molecular Formula	C48H96NO8P
Molecular Weight	846.26 g/mol
Synonyms	1,2-Diarachidoyl-sn-glycero-3-phosphocholine; DAPC; PC(20:0/20:0); Phosphatidylcholine(20:0/20:0); 1,2-Dieicosanoylphosphatidylcholine; L-α-Phosphatidylcholine, 1,2-dieicosanoyl-; 1,2-Di-O-eicosanoyl-sn-glycero-3-phosphocholine; 3-sn-Phosphatidylcholine, 1,2-diarachidoyl-
EINECS	Contact for details

Quality Control

Our 1,2-Dieicosanoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and cGMP-grade applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic (moisture-sensitive) nature. For long-term storage, desiccate. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 98.0%
Solubility	Soluble in chloroform, ethanol; insoluble in water
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.