Description

Rifapentine CAS NO 61379-65-5 is a semisynthetic antibiotic belonging to the rifamycin class, specifically developed for its potent activity against *Mycobacterium tuberculosis*. This compound is a critical active pharmaceutical ingredient (API) valued for its extended half-life, which supports less frequent dosing regimens. It is primarily required by pharmaceutical manufacturers and research institutions engaged in developing and producing advanced tuberculosis treatments, particularly for drug-susceptible and latent TB infections.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of anti-tuberculosis drugs.
• Key component in fixed-dose combination therapies for pulmonary tuberculosis.
• Use in the development of treatments for latent tuberculosis infection (LTBI).
• Reference standard in analytical and quality control laboratories for HPLC and spectrometry.
• Intermediate in pharmaceutical research for novel antimicrobial agents.
• Biochemical research tool for studying bacterial RNA polymerase inhibition.

Basic Information

Product Name	Rifapentine
CAS No.	61379-65-5
Molecular Formula	C47H64N4O12
Molecular Weight	877.03 g/mol
Synonyms	Rifapentine; 3-[[(4-Cyclopentyl-1-piperazinyl)imino]methyl]rifamycin; Rifapentine USP; Priftin; DL 473; Cyclopentylrifamycin; Rifapentinum; Rifapentina
EINECS	Contact for details

Quality Control

Our Rifapentine is manufactured and tested to meet stringent pharmacopeial standards. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC, to ensure compliance with specifications such as USP monograph requirements. A Certificate of Analysis (COA) documenting purity, related substances, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and quality assurance for our B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Reddish-brown to brown powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Complies with USP <61> test criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.