Description

Dimyristoylphosphatidylglycerol is a synthetic, saturated phospholipid widely utilized as a critical excipient and functional component in advanced pharmaceutical formulations. Its primary value lies in its ability to form stable, lamellar bilayer structures, making it indispensable for creating controlled-release drug delivery systems and enhancing the stability of sensitive active ingredients. This high-purity lipid is essential for manufacturers in the pharmaceutical, biotechnology, and advanced cosmetics industries developing liposomal therapeutics, vaccines, and high-performance dermal products.

Application

• Liposomal Drug Delivery Systems: A key component for formulating stable liposomes used to encapsulate and target the delivery of anticancer drugs, antifungals, and genetic material.
• Vaccine Adjuvants and Platforms: Employed in the development of lipid-based adjuvant systems and as a structural element in lipid nanoparticle (LNP) platforms for mRNA and other novel vaccines.
• Biomimetic Membrane Models: Used in research to create synthetic membranes for studying protein-lipid interactions, membrane permeability, and biophysical properties.
• Pulmonary Surfactants: Investigated as a component in synthetic lung surfactant formulations for the treatment of respiratory distress syndrome.
• Advanced Cosmetic Formulations: Incorporated into high-end skincare products like nanosomes and niosomes for enhanced penetration and stabilization of active compounds (e.g., vitamins, antioxidants).
• Diagnostic Reagents: Serves as a coating or functional layer in various diagnostic assays and biosensors.

Basic Information

Product Name	Dimyristoylphosphatidylglycerol
CAS No.	61361-72-6
Molecular Formula	C36H71O10P
Molecular Weight	694.91 g/mol
Synonyms	1,2-Dimyristoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt); DMPG; 14:0 PG; Phosphatidylglycerol (14:0/14:0); PG(28:0); 1,2-Ditetradecanoyl-sn-glycero-3-phosphoglycerol; 3-sn-Phosphatidyl-1'-sn-glycerol (Dimyristoyl); L-α-Phosphatidylglycerol (Dimyristoyl)
EINECS	Contact for details

Quality Control

Our Dimyristoylphosphatidylglycerol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and related substances, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (TLC)	Single spot
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 10 ppm
Residual Solvents	Meets ICH guidelines
Phase Transition Temp (Tm)	~23°C (Typical)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.