Description

(1Ar,4R,7R,7Ar,10As,10Br)-2,3,4,5,6,7,7A,8,10A,10B-Decahydro-7-Acetoxy-4-Hydroperoxy-1A-Methyl-5,8-Bis(Methylene)Oxireno[9,10]Cyclodeca[1,2-B]Furan-9(1Ah)-One is a complex, highly functionalized sesquiterpene lactone derivative, valued for its intricate molecular architecture and reactive functional groups. This compound serves as a critical advanced synthetic intermediate and a scaffold for novel chemical entities in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, fine chemical, and life science sectors for developing new active ingredients and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Medicinal Chemistry Research: Used as a core scaffold for library synthesis and SAR (Structure-Activity Relationship) studies due to its multiple reactive sites.
• Natural Product Synthesis: Serves as a sophisticated intermediate in the total synthesis of complex natural products and their analogs.
• Agrochemical Development: Investigated as a precursor for novel bioactive compounds with potential herbicidal or insecticidal properties.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and enzyme functions.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial-scale production of high-value specialty chemicals.

Basic Information

Product Name	(1Ar,4R,7R,7Ar,10As,10Br)-2,3,4,5,6,7,7A,8,10A,10B-Decahydro-7-Acetoxy-4-Hydroperoxy-1A-Methyl-5,8-Bis(Methylene)Oxireno[9,10]Cyclodeca[1,2-B]Furan-9(1Ah)-One
CAS No.	61228-73-7
Molecular Formula	C₁₇H₂₀O₆
Molecular Weight	320.34 g/mol
Synonyms	7-Acetoxy-4-hydroperoxy-1a-methyl-5,8-bis(methylene)oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one; Parthenolide derivative; Parthenolide hydroperoxide acetate; 4-Hydroperoxyparthenolide 7-acetate; Sesquiterpene lactone hydroperoxide; Oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one derivative; CAS 61228-73-7
EINECS	Contact for details

Quality Control

Every batch of our (1Ar,4R,7R,7Ar,10As,10Br)-2,3,4,5,6,7,7A,8,10A,10B-Decahydro-7-Acetoxy-4-Hydroperoxy-1A-Methyl-5,8-Bis(Methylene)Oxireno[9,10]Cyclodeca[1,2-B]Furan-9(1Ah)-One is produced and controlled under a strict Quality Management System. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to minimize degradation due to its light-sensitive and easily oxidized nature. Allow the container to reach room temperature in a desiccator before opening to prevent moisture condensation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Single Unknown Impurity	≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.