Description

(1S)-1α-(β-D-Glucopyranosyloxy)-1,4Aα,5,7Aα-Tetrahydro-7-Hydroxymethyl-Cyclopenta[C]Pyran-4-Carbaldehyde is a specialized glycosidic compound of significant interest in advanced organic synthesis and pharmaceutical research. Its complex structure, featuring a fused cyclopentapyran core linked to a glucose moiety, makes it a valuable chiral building block and a potential precursor for bioactive molecules. This high-purity intermediate is primarily sought by research institutions and development laboratories in the pharmaceutical, agrochemical, and fine chemical sectors for the synthesis of novel compounds and process development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex natural product analogs.
• Glycoscience Research: Used as a standard or substrate in enzymatic and chemical glycosylation studies to understand sugar chemistry and develop new synthetic methodologies.
• Fine Chemical Synthesis: Acts as a sophisticated building block for constructing complex molecular architectures in custom synthesis and contract research organizations (CROs).
• Agrochemical Development: Investigated as a potential intermediate for novel, biologically active compounds in crop protection research.
• Bioconjugate Chemistry: Utilized in the development of antibody-drug conjugates (ADCs) or other targeted delivery systems where specific glycosylation is required.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic chemistry, catalysis, and medicinal chemistry.

Basic Information

Product Name	(1S)-1α-(β-D-Glucopyranosyloxy)-1,4Aα,5,7Aα-Tetrahydro-7-Hydroxymethyl-Cyclopenta[C]Pyran-4-Carbaldehyde
CAS No.	61081-59-2
Molecular Formula	C₁₆H₂₂O₉
Molecular Weight	358.34 g/mol
Synonyms	7-(Hydroxymethyl)-1,4a,5,7a-tetrahydro-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxycyclopenta[c]pyran-4-carbaldehyde; (1S,4aS,7aR)-1-(β-D-Glucopyranosyloxy)-1,4a,5,7a-tetrahydro-7-(hydroxymethyl)cyclopenta[c]pyran-4-carbaldehyde; Glucosyloxy-tetrahydro-hydroxymethyl-cyclopentapyran-carbaldehyde; CAS 61081-59-2; 1-(β-D-Glucopyranosyloxy)-7-(hydroxymethyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carbaldehyde; A glycosylated cyclopentapyran derivative.
EINECS	Contact for details

Quality Control

Our (1S)-1α-(β-D-Glucopyranosyloxy)-1,4Aα,5,7Aα-Tetrahydro-7-Hydroxymethyl-Cyclopenta[C]Pyran-4-Carbaldehyde is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and structural confirmation via NMR and MS, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opened for prolonged periods to prevent oxidation and moisture uptake. Keep the container tightly sealed after each use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.