Description

(5R)-3-[[2-(Acetylamino)Ethyl]Thio]-6α-[(S)-1-(Sulfooxy)Ethyl]-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid Disodium Salt is a high-purity, advanced pharmaceutical intermediate belonging to the β-lactam class of compounds. This compound is critical for the synthesis of next-generation antibiotics, offering a sophisticated chemical backbone for targeted therapeutic development. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel anti-infective agents and specialized fine chemical synthesis.

Application

• Key Intermediate for β-Lactam Antibiotics: Serves as a crucial building block in the synthesis of advanced cephalosporin and penem-class antibiotics.
• Pharmaceutical Research & Development (R&D): Used in medicinal chemistry for the discovery and optimization of new antibacterial compounds with improved efficacy and resistance profiles.
• Process Chemistry & Scale-Up: Employed in the development and optimization of commercial-scale manufacturing routes for active pharmaceutical ingredients (APIs).
• Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical production.
• Biochemical Research: Applied in studies investigating bacterial cell wall synthesis and the mechanisms of action of β-lactam drugs.

Basic Information

Product Name	(5R)-3-[[2-(Acetylamino)Ethyl]Thio]-6α-[(S)-1-(Sulfooxy)Ethyl]-7-Oxo-1-Azabicyclo[3.2.0]Hept-2-Ene-2-Carboxylic Acid Disodium Salt
CAS No.	61036-81-5
Molecular Formula	C14H18N2Na2O8S2
Molecular Weight	460.40 g/mol
Synonyms	Disodium (5R,6S)-3-[(2-acetamidoethyl)thio]-6-[(1R)-1-(sulfooxy)ethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate; 6β-(1-Hydroxyethyl)-2-carboxy-2-penem-3-carboxylic Acid Disodium Salt Derivative; A β-lactam antibiotic intermediate; Penem derivative disodium salt; (5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[[2-(acetylamino)ethyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid disodium salt sulfate; SQ 27,246 Disodium Salt; Sulopenem related compound intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict cGMP (current Good Manufacturing Practice) guidelines to ensure batch-to-batch consistency and traceability. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles against stringent internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.