Description

1 Alpha,24-Dihydroxyvitamin D3 is a biologically active metabolite of Vitamin D3, also known as calcifediol. This compound is a critical intermediate in the vitamin D endocrine system, playing a key role in calcium and phosphate homeostasis. It is primarily utilized in advanced pharmaceutical research and development, particularly for metabolic bone disease studies and the synthesis of more potent vitamin D analogs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active vitamin D hormone analogs and other therapeutic agents.
• Biochemical Research: Used as a reference standard and active compound in studies of vitamin D metabolism, receptor binding, and gene regulation.
• Cell Culture & In Vitro Studies: Employed in research models to investigate bone mineralization, cell differentiation, and immune modulation.
• Metabolic Pathway Analysis: Essential for studying the 24-hydroxylation pathway of vitamin D activation and catabolism.
• Nutraceutical Development: Investigated for potential applications in specialized dietary supplements targeting bone health.

Basic Information

Product Name	1 Alpha,24-Dihydroxyvitamin D3
CAS No.	60965-80-2
Molecular Formula	C27H44O3
Molecular Weight	416.64 g/mol
Synonyms	1α,24-Dihydroxycholecalciferol; 1α,24-Dihydroxyvitamin D3; 24-Hydroxycalcidiol; (5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1α,3β,24-triol; 1α,24(OH)2D3; 24-Hydroxy-1α-hydroxyvitamin D3
EINECS	Contact for details

Quality Control

Our 1 Alpha,24-Dihydroxyvitamin D3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C (refrigerated) or as specified on the label or COA. This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep the container tightly sealed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.