Description

4-Hydroxypiperidinocyclohexyl Carbonitrile is a specialized organic compound featuring a unique piperidine-cyclohexane hybrid structure with both hydroxyl and nitrile functional groups. This molecular architecture makes it a valuable and versatile chemical intermediate for advanced synthesis in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its complex heterocyclic core.
• Chemical Research: Serves as a versatile precursor in organic chemistry for constructing piperidine and cyclohexane derivatives with specific stereochemistry.
• Ligand and Catalyst Development: The hydroxyl and nitrile groups can be modified to create novel ligands for metal catalysis or organocatalysts.
• Material Science Precursor: Potential use in the development of specialty polymers or advanced organic materials requiring rigid, functionalized monomers.

Basic Information

Product Name	4-Hydroxypiperidinocyclohexyl Carbonitrile
CAS No.	60756-86-7
Molecular Formula	C12H20N2O
Molecular Weight	208.30 g/mol
Synonyms	4-(Piperidin-4-yloxy)cyclohexanecarbonitrile; 4-(4-Piperidyloxy)cyclohexanecarbonitrile; Cyclohexanecarbonitrile, 4-(4-piperidinyloxy)-; 4-(Piperidin-4-yloxy)cyclohexane-1-carbonitrile; 4-Hydroxy-1-piperidinecyclohexanecarbonitrile; 4-Piperidinol, 4-cyano-1-cyclohexyl ether; 4-Cyclohexyloxypiperidine-4-carbonitrile (incorrect but common search variant)
EINECS	Contact for details

Quality Control

Every batch of 4-Hydroxypiperidinocyclohexyl Carbonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.