Description

5-Amino-2-(4-Methyl-Piperazin-1-Yl)-Benzamide is a high-purity, advanced pharmaceutical intermediate featuring a benzamide core substituted with amino and methylpiperazinyl groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially kinase inhibitors and receptor antagonists.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production route for complex APIs targeting central nervous system (CNS) and oncological disorders.
• Bioconjugation & Probe Development: The amino group allows for functionalization, making it suitable for creating diagnostic probes or targeted delivery systems.

Basic Information

Product Name	5-Amino-2-(4-Methyl-Piperazin-1-Yl)-Benzamide
CAS No.	60587-53-3
Molecular Formula	C12H19N5O
Molecular Weight	249.31 g/mol
Synonyms	5-Amino-2-(4-methyl-1-piperazinyl)benzamide; 2-(4-Methylpiperazin-1-yl)-5-aminobenzamide; 5-Amino-N-(4-methylpiperazin-1-yl)benzamide; Benzamide, 5-amino-2-(4-methyl-1-piperazinyl)-; 60587-53-3; UNII-9J7K7C8R4J; 9J7K7C8R4J
EINECS	Contact for details

Quality Control

Our 5-Amino-2-(4-Methyl-Piperazin-1-Yl)-Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.