Description

1,2-Didecanoyl-Sn-Glycerol is a synthetic, enantiomerically pure diacylglycerol (DAG) with defined stereochemistry at the sn-2 position. This compound serves as a critical high-purity biochemical intermediate and model compound for lipid research and synthesis. It is essential for researchers and manufacturers in the pharmaceutical, cosmetic, and specialty chemical industries who require precise lipid structures for drug delivery systems, biomembrane studies, and the synthesis of complex phospholipids.

Application

• Pharmaceutical Research & Drug Delivery: As a key synthetic intermediate for the preparation of phospholipids used in liposomal formulations and nanoparticle drug carriers.
• Biochemical & Metabolic Studies: Used as a substrate or standard in enzymatic assays to study diacylglycerol kinases, lipases, and lipid signaling pathways.
• Cosmetic Ingredient Synthesis: Serves as a building block for synthesizing skin-compatible emulsifiers and moisturizing agents with specific structural properties.
• Model Membrane Systems: Employed in biophysical research to create defined lipid bilayers for studying membrane protein interactions and permeability.
• Chemical Synthesis: Acts as a chiral starting material or protecting group in the stereoselective synthesis of more complex glycerolipids and glycolipids.
• Reference Standard: Used as a high-purity analytical standard in chromatography (HPLC, GC) for quality control and method development in lipid analysis.

Basic Information

Item	Detail
Product Name	1,2-Didecanoyl-Sn-Glycerol
CAS No.	60514-49-0
Molecular Formula	C23H44O5
Molecular Weight	400.60 g/mol
Synonyms	1,2-Dicaprinoyl-sn-glycerol; 1,2-Didecanoyl-rac-glycerol; sn-1,2-Didecanoylglycerol; Decanoic acid, 1,1'-[1-[(1S)-2,3-dihydroxypropoxy]-1-methyl-1,2-ethanediyl] ester; rac-1,2-Didecanoylglycerol; 1,2-Di-O-decanoyl-sn-glycerol; DAG(10:0/10:0); Glycerol 1,2-didecanoate
EINECS	Contact for details

Quality Control

Our 1,2-Didecanoyl-Sn-Glycerol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure identity, potency, and consistency. Certificates of Analysis (COA) documenting purity, enantiomeric excess, and impurity profiles are provided and available upon request, supporting compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% sn-1,2 isomer
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.