Description

3α,7α-Bis(Acetyloxy)-5β-Cholestan-26-Oic Acid Methyl Ester is a key synthetic intermediate in the production of bile acids and related steroidal compounds. This high-purity intermediate is critical for ensuring the quality and consistency of downstream pharmaceutical and research products. It is primarily utilized by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors for the development of therapeutic agents and biochemical research.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of therapeutic bile acids such as ursodeoxycholic acid (UDCA) and chenodeoxycholic acid (CDCA).
• Biochemical Research: Used as a standard or precursor in metabolic pathway studies, enzyme inhibition assays, and investigations into cholesterol metabolism.
• Fine Chemical Synthesis: Serves as a versatile chiral starting material for the preparation of complex steroidal derivatives with modified biological activity.
• Reference Standard: Employed as a high-purity analytical reference standard in quality control (QC) and quality assurance (QA) laboratories for HPLC and GC methods.
• Academic & Industrial R&D: Facilitates discovery chemistry and process development for new drug candidates and specialty chemicals within steroidal frameworks.

Basic Information

Product Name	3α,7α-Bis(Acetyloxy)-5β-Cholestan-26-Oic Acid Methyl Ester
CAS No.	60354-52-1
Molecular Formula	C32H52O6
Molecular Weight	532.76 g/mol
Synonyms	Methyl 3α,7α-Diacetoxy-5β-cholan-24-oate; Methyl 3α,7α-Diacetoxy-5β-cholestan-26-oate; 5β-Cholestan-26-oic acid, 3α,7α-bis(acetyloxy)-, methyl ester; 3α,7α-Diacetoxy-5β-cholan-24-oic Acid Methyl Ester; Chenodeoxycholic Acid 3,7-Diacetate Methyl Ester; CDCA Diacetate Methyl Ester; CAS 60354-52-1
EINECS	Contact for details

Quality Control

Our 3α,7α-Bis(Acetyloxy)-5β-Cholestan-26-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for use as a pharmaceutical intermediate. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.