Description

3β-Hydroxycostunolide is a bioactive sesquiterpene lactone, a key intermediate and reference standard in natural product research and pharmaceutical development. This compound is valued for its role in studying anti-inflammatory and cytotoxic pathways, offering significant potential for therapeutic agent discovery. It is primarily sought by research institutions, pharmaceutical R&D departments, and manufacturers of high-purity botanical extracts and fine chemicals.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and intermediate in the synthesis and study of novel anti-inflammatory and anticancer agents.
• Natural Product Chemistry: Used as a high-purity analytical standard for the identification and quantification of sesquiterpene lactones in complex botanical matrices.
• Biochemical Assays: Employed in in vitro and cellular assays to investigate mechanisms of action related to NF-κB inhibition and apoptosis induction.
• Academic Research: Essential for university and institutional labs conducting studies on the structure-activity relationships of terpenoids.
• Fine Chemical Synthesis: Acts as a chiral building block for the semi-synthesis of more complex, biologically active molecules.
• Quality Control for Herbal Extracts: Utilized by manufacturers to standardize and validate the potency of extracts containing costunolide and related compounds.

Basic Information

Product Name	3β-Hydroxycostunolide
CAS No.	60268-40-8
Molecular Formula	C₁₅H₂₂O₃
Molecular Weight	250.33 g/mol
Synonyms	3β-Hydroxycostunolide; 3β-Hydroxy-11,13-dihydrocostunolide; 3β-Hydroxy-4,5-dihydrocostunolide; (3β,4α,5α,6β,7α,8α)-3-Hydroxy-4,5-epoxy-6,7-germacran-12,8-olide; 3β-Hydroxy-4α,5α-epoxy-6β,7α-germacran-12,8α-olide; 3-Hydroxycostunolide; 3β-Hydroxy-4,5-epoxygermacra-1(10),11(13)-dien-12,8-olide
EINECS	Contact for details

Quality Control

Our 3β-Hydroxycostunolide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.