Description

3-[2-[(4-Cinnamyl-1-Piperazinyl)Methyl]-1H-Benzimidazol-1-Yl]-1-(2-Furyl)Propan-1-One Dimaleate is a high-purity, non-salt organic compound with a complex heterocyclic structure, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in enabling the synthesis of novel therapeutic agents, particularly those targeting neurological and receptor-based pathways. This product is essential for pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in the discovery and process development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzimidazole and piperazine-based drug candidates.
• Neurological Research: Used in the development of compounds for studying and targeting specific neurotransmitter receptors.
• Chemical Biology Probes: Acts as a precursor for creating specialized molecular probes to investigate protein-ligand interactions.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of target APIs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Preclinical Development: Utilized in the preparation of compounds for pharmacological screening and early-stage toxicology studies.

Basic Information

Product Name	3-[2-[(4-Cinnamyl-1-Piperazinyl)Methyl]-1H-Benzimidazol-1-Yl]-1-(2-Furyl)Propan-1-One Dimaleate
CAS No.	60248-24-0
Molecular Formula	C₃₃H₃₄N₄O₇
Molecular Weight	598.65 g/mol
Synonyms	1-(2-Furyl)-3-[2-[(4-cinnamyl-1-piperazinyl)methyl]-1H-benzimidazol-1-yl]-1-propanone dimaleate; 1-(2-Furyl)-3-[2-[[4-(3-phenyl-2-propen-1-yl)-1-piperazinyl]methyl]-1H-benzimidazol-1-yl]-1-propanone (E)-2-butenedioate (1:2); 3-[2-[(4-Cinnamylpiperazin-1-yl)methyl]-1H-benzimidazol-1-yl]-1-(furan-2-yl)propan-1-one dimaleate; Fumarizine Impurity; Cinnarizine Related Compound; Contact for additional trade names and research codes.
EINECS	Contact for details

Quality Control

Our 3-[2-[(4-Cinnamyl-1-Piperazinyl)Methyl]-1H-Benzimidazol-1-Yl]-1-(2-Furyl)Propan-1-One Dimaleate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, generated using validated analytical methods including HPLC, NMR, and MS. We adhere to ICH guidelines for stability and impurity characterization to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.