Description

Methyl 3-Amino-6-Bromopyrazine-2-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique pyrazine core, functionalized with amino, bromo, and ester groups, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, including kinase inhibitors and other biologically relevant heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for creating functional organic materials, such as ligands for catalysts or components in electronic materials.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization due to the reactive bromine and amino groups.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	Methyl 3-Amino-6-Bromopyrazine-2-Carboxylate
CAS No.	6966-01-4
Molecular Formula	C6H6BrN3O2
Molecular Weight	232.04 g/mol
Synonyms	Methyl 3-amino-6-bromopyrazine-2-carboxylate; 6-Bromo-3-aminopyrazine-2-carboxylic acid methyl ester; 3-Amino-6-bromopyrazine-2-carboxylic acid methyl ester; Methyl 3-amino-6-brom-2-pyrazincarboxylat; 2-Pyrazinecarboxylic acid, 3-amino-6-bromo-, methyl ester; MBPC; 6966-01-4
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Amino-6-Bromopyrazine-2-Carboxylate is produced and tested under strict quality management systems. We ensure high chemical purity and lot-to-lot consistency through advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed immediately after use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.