Description

(1S,5Aβ,8Aα,9S)-Octahydro-1,3,3,6α-Tetramethyl-1,4α-Ethano-1H-Cyclopent[C]Oxepine-8β,9-Diol is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. Its complex, polycyclic structure with multiple chiral centers makes it a valuable building block for constructing intricate molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical developers for applications in medicinal chemistry and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for complex therapeutic agents.
• Medicinal Chemistry Research: Used as a sophisticated scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fragrance and Flavor Synthesis: Its complex, oxygenated bicyclic structure makes it a potential intermediate for creating novel, high-value aroma chemicals and flavorants.
• Advanced Material Science: Can be utilized in the synthesis of specialized polymers or ligands where its rigid, multi-functional framework imparts specific properties.
• Academic and R&D Laboratories: Employed in methodological studies and as a model compound for developing new synthetic transformations and catalytic processes.

Basic Information

Product Name	(1S,5Aβ,8Aα,9S)-Octahydro-1,3,3,6α-Tetramethyl-1,4α-Ethano-1H-Cyclopent[C]Oxepine-8β,9-Diol
CAS No.	6894-57-1
Molecular Formula	C₁₅H₂₆O₃
Molecular Weight	254.37 g/mol
Synonyms	1,4α-Ethano-1H-cyclopent[c]oxepine-8β,9-diol, octahydro-1,3,3,6α-tetramethyl-, (1S,5aβ,8aα,9S)-; Ambrox; Ambroxide precursor; 8β,9-Dihydroxy-1,3,3,6α-tetramethyl-1,4α-ethanooctahydrocyclopent[c]oxepine; (1S,5aβ,8aα,9S)-Octahydro-1,3,3,6α-tetramethyl-1,4α-ethano-1H-cyclopent[c]oxepine-8β,9-diol; Dihydroambrox; A key intermediate for Ambroxide synthesis.
EINECS	Contact for details

Quality Control

Our (1S,5Aβ,8Aα,9S)-Octahydro-1,3,3,6α-Tetramethyl-1,4α-Ethano-1H-Cyclopent[C]Oxepine-8β,9-Diol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and stereochemical purity suitable for demanding R&D applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.