Description

All-Trans 3-Hydroxyretinol is a biologically active metabolite of Vitamin A, specifically a hydroxylated form of retinol. This compound is of significant interest in biochemical research and pharmaceutical development due to its role in cellular signaling and differentiation processes. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, nutraceutical, and advanced life science sectors for applications ranging from reference standards to active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of Vitamin A metabolites in drug development and quality control.
• Biochemical Research: Serves as a critical reagent in studies of retinoid metabolism, cellular differentiation, and gene expression regulation.
• Active Pharmaceutical Ingredient (API) Intermediate: Employed in the synthesis of specialized retinoid-based therapeutics.
• Nutraceutical Research: Investigated for its potential bioactivity and metabolic pathways in advanced dietary supplement formulations.
• Cell Culture & In Vitro Studies: Applied in media supplements to study its effects on specific cell lines and tissue models.
• Analytical Method Development: Acts as a high-purity calibrant for developing and validating HPLC, LC-MS, and other chromatographic assays.

Basic Information

Product Name	All-Trans 3-Hydroxyretinol
CAS No.	6890-93-3
Molecular Formula	C₂₀H₃₀O₂
Molecular Weight	302.45 g/mol
Synonyms	3-Hydroxyretinol; all-trans-3-Hydroxyretinol; Vitamin A Alcohol, 3-Hydroxy-; 3,4-Didehydroretinol; 3-Hydroxy Vitamin A; Retinol, 3-hydroxy-; (all-E)-3-Hydroxyretinol; 3-OH-Retinol
EINECS	Contact for details

Quality Control

Our All-Trans 3-Hydroxyretinol is produced and tested under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, UV), to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area Percent)
All-trans Isomer Content	≥ 90.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residues	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.