Description

3-Amino-6-Bromo-1H-Pyrazine-2-Thione is a heterocyclic organic compound featuring a pyrazine core functionalized with amino, bromo, and thione groups. This unique structure makes it a valuable and versatile chemical building block for advanced synthesis in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists for constructing complex molecules. Its reactivity profile allows for selective modifications, enabling the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in developing kinase inhibitors, antiviral agents, and other bioactive heterocycles.
• Agrochemical Research: Used to create new molecules for crop protection, including potential fungicides, herbicides, and plant growth regulators.
• Material Science: Serves as a building block for organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional organic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions due to the reactive bromine substituent.
• Dye & Pigment Intermediate: Utilized in the development of specialized dyes and pigments owing to its conjugated heterocyclic system.
• Academic & Contract Research: Essential for fundamental organic chemistry research and discovery projects in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	3-Amino-6-Bromo-1H-Pyrazine-2-Thione
CAS No.	6863-75-8
Molecular Formula	C4H4BrN3S
Molecular Weight	206.06 g/mol
Synonyms	6-Bromo-3-amino-2-mercaptopyrazine; 3-Amino-6-bromo-2-mercaptopyrazine; 6-Bromo-3-aminopyrazine-2-thiol; 2-Thioxo-3-amino-6-bromo-1,2-dihydropyrazine; 3-Amino-6-bromo-1H-pyrazine-2(3H)-thione; 6-Bromo-3-pyrazinamine-2-thione; 3-Amino-6-bromopyrazine-2-thiol
EINECS	Contact for details

Quality Control

Our 3-Amino-6-Bromo-1H-Pyrazine-2-Thione is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure high consistency and reliability for your research and development processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brown powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.