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3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-Pentadecaoxaheptatetracontane-1,47-Diol CAS NO 6812-36-8


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CAS No.:6812-36-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-Pentadecaoxaheptatetracontane-1,47-Diol is a high-purity polyethylene glycol (PEG) derivative, specifically a long-chain PEG diol, known for its exceptional hydrophilicity and biocompatibility. This compound is a critical building block for creating advanced, water-soluble polymers and functional materials with precise molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors who require reliable, high-quality PEGylation reagents and polymer precursors.

Application

  • Pharmaceutical PEGylation: A key linker or spacer arm for conjugating therapeutic proteins, peptides, and oligonucleotides to improve solubility, stability, and circulation half-life.
  • Bioconjugation Chemistry: Serves as a hydrophilic spacer in the synthesis of diagnostic reagents, antibody-drug conjugates (ADCs), and biosensors.
  • Polymer Synthesis: A macro-initiator or monomer for producing block copolymers, hydrogels, and non-ionic surfactants with tailored properties.
  • Surface Modification: Used to create anti-fouling, protein-resistant coatings on medical devices, nanoparticles, and chromatographic media.
  • Drug Delivery Systems: Incorporated into the matrix of micelles, liposomes, and dendrimers to enhance biocompatibility and targeted delivery.
  • Cosmetic & Personal Care: Functions as a humectant and conditioning agent in high-performance skincare formulations.
  • Lubricants & Functional Fluids: Employed as a base or additive in specialty lubricants and heat transfer fluids.

Basic Information

Product Name 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-Pentadecaoxaheptatetracontane-1,47-Diol
CAS No. 6812-36-8
Molecular Formula C34H70O17
Molecular Weight 726.90 g/mol
Synonyms PEG 1000 Diol; Polyethylene Glycol 1000 Diol; α,ω-Dihydroxypoly(oxy-1,2-ethanediyl); Poly(oxy-1,2-ethanediyl), α-hydro-ω-hydroxy-; Poly(ethylene oxide) diol (MW ~1000); 1,47-Dihydroxy-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxaheptatetracontane; Polyoxyethylene diol; HO-PEG1000-OH
EINECS Contact for details

Quality Control

Our 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-Pentadecaoxaheptatetracontane-1,47-Diol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) documenting purity, molecular weight distribution, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect product performance.

Specification

Item Specification
Appearance White waxy solid or viscous liquid
Identification (IR) Conforms to structure
Assay (by Titration) ≥ 95.0 %
Average Molecular Weight (GPC) 950 - 1050
Polydispersity Index (PDI) ≤ 1.05
Water Content (KF) ≤ 1.0 %
Hydroxyl Value Contact for details
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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