Description

1-Thiophen-2-Ylmethyl-Piperazine Dihydrochloride is a high-purity, versatile chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its piperazine-thiophene hybrid structure, which is a privileged scaffold for developing active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the bioactivity of the piperazine moiety.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the thiophene ring can contribute to specific biological activity.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Material Science: Acts as a monomer or functionalizing agent in the development of specialized polymers and advanced materials.

Basic Information

Product Name	1-Thiophen-2-Ylmethyl-Piperazine Dihydrochloride
CAS No.	6803-90-3
Molecular Formula	C10H15N2S • 2HCl
Molecular Weight	283.22 g/mol (for dihydrochloride salt)
Synonyms	1-[(Thiophen-2-yl)methyl]piperazine dihydrochloride; 2-[(Piperazin-1-yl)methyl]thiophene dihydrochloride; 1-(Thiophen-2-ylmethyl)piperazine dihydrochloride; 1-(2-Thienylmethyl)piperazine dihydrochloride; 1-(Thiophene-2-ylmethyl)piperazine hydrochloride (1:2); Piperazine, 1-[(2-thienyl)methyl]-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-Thiophen-2-Ylmethyl-Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.