Description

1-Hydroxy-1λ5-Phospholane 1-Oxide is a specialized organophosphorus compound featuring a unique five-membered phospholane ring structure. This heterocyclic phosphine oxide is valued as a versatile intermediate and ligand in advanced synthetic chemistry and catalysis. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic pathways.
• Catalyst Ligand Precursor: Used in the preparation of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Employed in the development of new-generation herbicides, insecticides, and plant growth regulators with improved efficacy.
• Material Science: Acts as a monomer or additive in the synthesis of specialty polymers, flame retardants, and advanced electronic materials.
• Chemical Synthesis: Functions as a phosphorylating agent or a stable phosphine oxide synthon in complex organic transformations.
• Academic & R&D: Utilized in universities and corporate research labs for studying reaction mechanisms and developing new synthetic methodologies.

Basic Information

Product Name	1-Hydroxy-1λ5-Phospholane 1-Oxide
CAS No.	6787-46-8
Molecular Formula	C₄H₉O₂P
Molecular Weight	120.09 g/mol
Synonyms	1-Hydroxyphospholane 1-oxide; 1-Hydroxyphospholane oxide; Phospholane-1-ol 1-oxide; 1-Hydroxy-1-phospholane 1-oxide; 1-Phospholanol 1-oxide; Tetrahydro-1-hydroxyphosphole 1-oxide; 1-Hydroxy-1λ⁵-phospholane-1-one; 1-Oxo-1-hydroxyphospholane
EINECS	Contact for details

Quality Control

Our production of 1-Hydroxy-1λ5-Phospholane 1-Oxide adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from advanced analytical techniques, including NMR, HPLC, and GC-MS. Our quality system supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.