Description

1-Palmitoyl-2-Oleoylphosphatidylcholine (POPC) is a high-purity, synthetic phospholipid with a defined fatty acid composition, serving as a critical building block for advanced biomimetic systems. Its consistent structure is essential for creating stable, well-defined lipid bilayers, making it indispensable for fundamental biophysical research and the development of sophisticated drug delivery platforms. This product is primarily utilized by researchers and formulators in the pharmaceutical, biotechnology, and advanced materials sectors who require precise control over membrane properties and formulation behavior.

Application

• Liposome & Nanoparticle Formulation: A primary component for constructing unilamellar vesicles (LUVs, SUVs) and solid lipid nanoparticles (SLNs) for drug and gene delivery.
• Biomembrane Research: Used as a standard or major constituent in model membrane systems (e.g., supported lipid bilayers, black lipid membranes) to study membrane fluidity, protein-lipid interactions, and permeability.
• Cell Culture & Reconstitution: Employed in serum-free media supplements and for the reconstitution of transmembrane proteins to maintain native functionality.
• Diagnostic Assays: Serves as a coating or matrix material in biosensors, lateral flow assays, and other diagnostic platforms to provide a biocompatible interface.
• Cosmetic Actives Carrier: Forms the core of nanocarriers for the targeted and sustained delivery of active ingredients (vitamins, antioxidants) in high-end cosmetic formulations.
• Reference Standard: Acts as a high-purity analytical standard for quality control in pharmaceutical lipid analysis and regulatory submissions.

Basic Information

Product Name	1-Palmitoyl-2-Oleoylphosphatidylcholine
CAS No.	6753-55-5
Molecular Formula	C42H82NO8P
Molecular Weight	760.08 g/mol
Synonyms	POPC; 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine; (2R)-2-[(9Z)-Octadec-9-enoyloxy]-3-(palmitoyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate; Phosphatidylcholine (16:0/18:1); PC(16:0/18:1(9Z)); 3-sn-Phosphatidylcholine, 1-palmitoyl-2-oleoyl-; 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; L-α-Phosphatidylcholine, 1-palmitoyl-2-oleoyl-
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Oleoylphosphatidylcholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and fatty acid profile confirmation, to ensure it meets the stringent requirements for research and formulation. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. Under these conditions, the product is typically stable for at least two years. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white waxy solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (Total Phospholipid)
Fatty Acid Composition (GC)	Palmitic Acid (C16:0): 45-55%; Oleic Acid (C18:1): 45-55%
Lyso-Impurities (HPLC)	≤ 1.0%
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.