Description

(3Ar,7Aα,9Aα)-Dodecahydro-5β,6β-Diacetoxy-4Aβ,8β-Dimethyl-3-Methyleneazuleno[6,5-B]Furan-2-One is a high-purity, complex sesquiterpene lactone derivative with significant synthetic utility. This compound serves as a critical advanced intermediate for the synthesis of novel bioactive molecules and complex natural product analogs. It is primarily needed by pharmaceutical R&D teams, academic research laboratories, and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel sesquiterpene-based drug candidates with potential anti-inflammatory or anticancer activity.
• Organic Synthesis Research: Used in academic and industrial labs to study complex cyclization reactions and develop new synthetic methodologies.
• Natural Product Analog Development: Serves as a core scaffold for creating analogs of naturally occurring guaianolides and other sesquiterpene lactones.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and enzyme interactions.
• Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals for high-value applications.

Basic Information

Product Name	(3Ar,7Aα,9Aα)-Dodecahydro-5β,6β-Diacetoxy-4Aβ,8β-Dimethyl-3-Methyleneazuleno[6,5-B]Furan-2-One
CAS No.	6605-89-6
Molecular Formula	C21H28O6
Molecular Weight	376.45 g/mol
Synonyms	5β,6β-Diacetoxy-4α,8β-dimethyl-3-methylenedodecahydroazuleno[6,5-b]furan-2(3H)-one; Dihydro-5β,6β-diacetoxy-4α,8β-dimethyl-3-methylenezuleno[6,5-b]furan-2-one; Guaianolide derivative; Sesquiterpene lactone diacetate; Azuleno[6,5-b]furan-2-one, dodecahydro-5β,6β-diacetoxy-4α,8β-dimethyl-3-methylene-, (3aR,4S,5S,6S,7aS,9aS,9bR)-rel-; (rel-(3aR,4S,5S,6S,7aS,9aS,9bR))-Dodecahydro-5,6-diacetoxy-4,8-dimethyl-3-methylenezuleno[6,5-b]furan-2-one
EINECS	Contact for details

Quality Control

Our (3Ar,7Aα,9Aα)-Dodecahydro-5β,6β-Diacetoxy-4Aβ,8β-Dimethyl-3-Methyleneazuleno[6,5-B]Furan-2-One is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full chromatographic data are available upon request, providing traceability and compliance support for your research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled under inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.