Description

(3Ar,7Aα,9Aα)-Dodecahydro-5β,6β-Dihydroxy-4Aβ,8β-Dimethyl-3-Methyleneazuleno[6,5-B]Furan-2-One is a complex sesquiterpene lactone derivative, a high-purity synthetic intermediate of significant interest in advanced organic synthesis. Its intricate polycyclic structure with multiple stereocenters makes it a valuable chiral building block for pharmaceutical research and development. This compound is primarily sought by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other biologically active molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the multi-step synthesis of complex drug candidates, particularly in oncology and anti-inflammatory therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold or starting material for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Asymmetric Synthesis: Employed as a sophisticated building block in stereoselective reactions to construct molecules with defined three-dimensional architecture.
• Reference Standard: Utilized as an analytical standard for quality control and method development in laboratories manufacturing or researching related compounds.
• Academic Research: Applied in university and institutional labs for studies in total synthesis, natural product chemistry, and reaction methodology development.

Basic Information

Product Name	(3Ar,7Aα,9Aα)-Dodecahydro-5β,6β-Dihydroxy-4Aβ,8β-Dimethyl-3-Methyleneazuleno[6,5-B]Furan-2-One
CAS No.	6605-88-5
Molecular Formula	C₁₅H₂₂O₄
Molecular Weight	266.33 g/mol
Synonyms	Dihydroxy-dimethyl-methyleneazuleno-furanone; Azuleno[6,5-b]furan-2(3H)-one, dodecahydro-5,6-dihydroxy-4,8-dimethyl-3-methylene-, (3aR,4S,5S,6S,7aR,9aS,9bR)-; (3aR,4S,5S,6S,7aR,9aS,9bR)-Dodecahydro-5,6-dihydroxy-4,8-dimethyl-3-methylideneazuleno[6,5-b]furan-2-one; CAS 6605-88-5
EINECS	Contact for details

Quality Control

Our (3Ar,7Aα,9Aα)-Dodecahydro-5β,6β-Dihydroxy-4Aβ,8β-Dimethyl-3-Methyleneazuleno[6,5-B]Furan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral assays, to ensure it meets the exacting standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.