Description

4-(Toluene-4-Sulfonyl)-Piperazin-1-Ylamine CAS NO 6591-95-3 is a high-purity, functionalized piperazine derivative featuring a tosyl-protected amine group. This compound serves as a versatile and critical building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its piperazine core for bioactivity.
• Chemical Research & Development: Employed as a versatile scaffold for constructing combinatorial libraries and exploring structure-activity relationships (SAR) in medicinal chemistry.
• Fine Chemical Production: Acts as a building block for specialty chemicals, dyes, and functional materials requiring specific amine-protected intermediates.
• Ligand and Catalyst Development: The sulfonamide and amine functionalities make it useful for creating novel ligands in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-(Toluene-4-Sulfonyl)-Piperazin-1-Ylamine
CAS No.	6591-95-3
Molecular Formula	C11H17N3O2S
Molecular Weight	255.34 g/mol
Synonyms	1-Amino-4-(p-tolylsulfonyl)piperazine; 4-(4-Methylphenyl)sulfonyl-1-piperazinamine; 1-Piperazinamine, 4-[(4-methylphenyl)sulfonyl]-; N-(4-Methylbenzenesulfonyl)piperazin-1-amine; Tosylpiperazinamine; 4-Tosyl-1-piperazinamine; 1-Amino-4-tosylpiperazine; 4-Aminopiperazine-1-sulfonic acid p-tolyl ester
EINECS	Contact for details

Quality Control

Our 4-(Toluene-4-Sulfonyl)-Piperazin-1-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.