Description

Piperazine, 1-(Trifluoroacetyl)- (7Ci,8Ci,9Ci) is a high-purity, trifluoroacetylated derivative of piperazine, serving as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the trifluoroacetyl protecting group and as a versatile intermediate for creating complex molecules with tailored properties. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and novel materials. CAS NO 6511-88-2.

Application

• Pharmaceutical Intermediate: Key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoroacetyl group can contribute to improved activity and environmental profile.
• Peptide Chemistry & Protecting Group: Serves as a reagent for the trifluoroacetylation of amines, acting as a protecting group in multi-step peptide and complex molecule synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers, ligands, and fluorinated organic compounds for advanced material applications.
• Chemical Research & Development: A versatile building block in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Item	Details
Product Name	Piperazine, 1-(Trifluoroacetyl)- (7Ci,8Ci,9Ci)
CAS No.	6511-88-2
Molecular Formula	C6H9F3N2O
Molecular Weight	182.15 g/mol
Synonyms	1-(Trifluoroacetyl)piperazine; N-(Trifluoroacetyl)piperazine; Piperazine, 1-(trifluoroacetyl)-; 1-Piperazinecarboxamide, N,N,N-trifluoro-; Trifluoroacetic acid piperazide; 6511-88-2; N-Trifluoroacetylpiperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(Trifluoroacetyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.