Description

5-o-Cinnamoylquinic Acid is a specialized cinnamic acid derivative and a key chlorogenic acid isomer. This high-purity compound is valued for its role as a bioactive reference standard and a critical intermediate in advanced research and development. It is primarily sought by professionals in the pharmaceutical, nutraceutical, and analytical chemistry sectors for applications requiring precise chemical characterization and bioactivity studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of related natural products and complex botanical extracts.
• Bioactivity & Mechanism Studies: Serves as a key intermediate or probe in research focused on antioxidant, anti-inflammatory, and metabolic regulatory pathways.
• Nutraceutical & Functional Food R&D: Employed in the development and standardization of health supplements derived from green coffee bean, honeysuckle, or other chlorogenic acid-rich sources.
• Analytical Chemistry: Essential for method development and validation in HPLC, LC-MS, and other chromatographic techniques for quantifying chlorogenic acids.
• Cosmeceutical Research: Investigated for its potential skin-beneficial properties, including UV protection and anti-aging effects, in advanced cosmetic formulations.

Basic Information

Product Name	5-o-Cinnamoylquinic Acid
CAS No.	6470-68-4
Molecular Formula	C17H20O9
Molecular Weight	368.34 g/mol
Synonyms	5-O-Cinnamoylquinic Acid; 5-CQA; 5-Caffeoylquinic Acid Isomer; 5-O-Caffeoylquinic Acid; Neochlorogenic Acid; 5-O-(3,4-Dihydroxycinnamoyl)quinic Acid; 5-O-Caffeoyl-1-quinic Acid; (1S,3R,4R,5R)-3-{[(2E)-3-(3,4-Dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexane-1-carboxylic Acid
EINECS	Contact for details

Quality Control

Every batch of 5-o-Cinnamoylquinic Acid is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements for research and development. A detailed Certificate of Analysis (COA) with HPLC purity, spectral data (IR, NMR, MS), and related substance profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals (as Pb)	≤20 ppm
Related Substances (HPLC)	Total impurities ≤5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.