Description

Lactucopicrin is a naturally occurring sesquiterpene lactone, a key bioactive constituent found in plants of the *Lactuca* genus. This compound is valued for its significant biological activity, making it a critical standard and reference material for research and quality control. It is primarily sought after by the pharmaceutical, nutraceutical, and botanical extract industries for applications in analytical research, product development, and standardization. Lactucopicrin CAS NO 6466-74-6 represents a high-purity phytochemical essential for advancing studies in natural product chemistry and pharmacology.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of lactucopicrin in drug substances and finished products.
• Botanical Extract Standardization: Serves as a quantitative marker for standardizing herbal extracts, particularly those derived from wild lettuce (*Lactuca virosa*), to ensure consistent potency and efficacy.
• Bioactivity and Pharmacological Research: Employed in preclinical studies to investigate its sedative, analgesic, and anti-inflammatory properties, supporting new drug discovery.
• Dietary Supplement Quality Control: Acts as an analytical standard for verifying the label claim and purity of lactucopicrin in finished nutraceutical and dietary supplement formulations.
• Academic and Analytical Chemistry: Utilized in university and commercial laboratories for method development, validation, and teaching purposes in natural product analysis.
• Cosmeceutical Research: Investigated for potential applications in topical formulations aimed at soothing skin or reducing irritation due to its bioactive profile.

Basic Information

Product Name	Lactucopicrin
CAS No.	6466-74-6
Molecular Formula	C23H22O7
Molecular Weight	410.42 g/mol
Synonyms	11β,13-Dihydrolactucin 8-O-(4-hydroxyphenylacetate); 11β,13-Dihydrolactucin 8-(4-hydroxybenzeneacetate); 8-(4-Hydroxyphenylacetyl)-11β,13-dihydrolactucin; Intybin; Lettucenin A; Lactucin 8-(4-hydroxybenzeneacetate) (dihydro); (8S,11R)-8-[[(4-Hydroxyphenyl)acetyl]oxy]-4,11-dihydroxy-11-methyl-3,14-dioxatricyclo[9.3.0.0²,⁴]tetradec-6-en-13-one
EINECS	Contact for details

Quality Control

Our Lactucopicrin is produced and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets high-purity standards suitable for research and analytical applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are available upon request for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term stability, consider storage at 2-8°C. The container should be kept in a well-ventilated area away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.