Description

Piperazine, 1-(Fluoroacetyl)- (7Ci,8Ci,9Ci) CAS NO 6442-83-7 is a specialized fluorinated piperazine derivative, a key building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate, enabling the introduction of both the piperazine scaffold and a reactive fluoroacetyl moiety into target molecules. It is primarily required by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom can enhance biological activity, metabolic stability, and lipophilicity.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes and labeled compounds for studying biochemical pathways and protein interactions.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with unique thermal or chemical resistance properties.
• Fluorine Chemistry Library Building: A valuable reagent for constructing diverse compound libraries in medicinal chemistry for high-throughput screening (HTS) campaigns.

Basic Information

Product Name	Piperazine, 1-(Fluoroacetyl)- (7Ci,8Ci,9Ci)
CAS No.	6442-83-7
Molecular Formula	C6H11FN2O
Molecular Weight	146.16 g/mol
Synonyms	1-Fluoroacetylpiperazine; N-Fluoroacetylpiperazine; 1-(Fluoroacetyl)piperazine; 1-Piperazineacetamide, N-fluoro-; Fluoroacetylpiperazine; N-(2-Fluoroacetyl)piperazine; 6442-83-7; 1-Fluoroacetyl-piperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 1-(Fluoroacetyl)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.