Description

Trichothecin is a potent mycotoxin belonging to the trichothecene family of sesquiterpenoid compounds. This compound is of significant interest in biochemical and pharmacological research due to its specific inhibitory effects on protein synthesis in eukaryotic cells. It serves as a critical reference standard and research tool for scientists in the fields of mycotoxicology, food safety, and the development of antifungal agents.

Application

• Mycotoxin Reference Standard: Primary use as an analytical standard for the identification and quantification of trichothecene mycotoxins in food, feed, and environmental samples via HPLC, LC-MS/MS, or ELISA methods.
• Biochemical Research: Used to study the mechanism of protein synthesis inhibition in eukaryotic cells, serving as a tool to investigate ribosome function and cellular stress responses.
• Antifungal Agent Research: Investigated for its natural fungicidal properties, providing a model compound for developing novel antifungal strategies and understanding fungal pathogenesis.
• Toxicology Studies: Essential for conducting safety assessments, understanding the toxicokinetics, and establishing exposure limits for trichothecene contaminants.
• Phytopathological Studies: Applied in plant science research to examine plant-pathogen interactions and the role of mycotoxins in plant disease development.
• Quality Control & Method Validation: Utilized by testing laboratories and manufacturers to validate analytical methods, calibrate equipment, and ensure the accuracy of mycotoxin detection protocols.

Basic Information

Product Name	Trichothecin
CAS No.	6379-69-7
Molecular Formula	C19H24O5
Molecular Weight	332.39 g/mol
Synonyms	Trichothecin; NSC 83291; (-)-Trichothecin; Trichothecin, (R-(R*,S*))-; (3α,4β,8α)-12,13-Epoxytrichothec-9-en-4-ol, 3-acetate 8-isovalerate; 4β-Hydroxy-12,13-epoxytrichothec-9-en-3α-yl acetate 8-isovalerate
EINECS	228-952-3

Quality Control

Our Trichothecin is produced and handled under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant guidelines for reference standard materials to support your analytical and research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere to minimize oxidation and ensure long-term stability. Allow the container to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.