Description

(E)-3-Iodo-2-Propenoic Acid is a high-value, unsaturated iodo-organic acid building block. This compound is essential for synthesizing complex molecules, particularly in pharmaceutical research and advanced material science, due to its reactive vinyl iodide and carboxylic acid functional groups. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in cross-coupling reactions like Heck, Suzuki, and Sonogashira couplings.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands and organometallic catalysts.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers with specific optical or electronic properties.
• Bioconjugation and Probe Synthesis: Useful for labeling biomolecules or creating fluorescent or radioactive probes for diagnostic and research applications.
• Academic and Industrial R&D: A versatile reagent for method development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	(E)-3-Iodo-2-Propenoic Acid
CAS No.	6372-02-7
Molecular Formula	C3H3IO2
Molecular Weight	197.96 g/mol
Synonyms	(E)-3-Iodoacrylic Acid; trans-3-Iodoacrylic Acid; 3-Iodo-2-propenoic acid, (E)-; (E)-3-Iodoprop-2-enoic Acid; trans-β-Iodoacrylic Acid; β-Iodoacrylic Acid; 3-Iodoacrylic Acid; Iodoacrylic Acid
EINECS	228-915-9

Quality Control

Our (E)-3-Iodo-2-Propenoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its light-sensitive nature and acidic character, containers should be kept sealed and handled in accordance with laboratory safety protocols for organic acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.