Description

n-Palmitoyl-D-Sphingomyelin is a high-purity, synthetic sphingolipid derivative, a critical component for advanced biomedical and biochemical research. This compound serves as a vital standard and reagent for studying membrane structure, lipid rafts, and cellular signaling pathways. It is essential for researchers and manufacturers in the pharmaceutical, cosmetic, and life science industries developing novel therapeutics and delivery systems.

Application

• Biomedical Research Standard: Used as a certified reference material for the quantification and qualification of sphingomyelin species in mass spectrometry and chromatography.
• Lipidomics & Metabolomics: A key analytical standard in lipid profiling studies to understand disease mechanisms related to lipid metabolism.
• Membrane Biophysics: Employed in the construction of model lipid bilayers and liposomes to study membrane fluidity, permeability, and protein-lipid interactions.
• Drug Delivery Systems: A component in the formulation of advanced liposomal and nanoparticle-based carriers for targeted drug delivery.
• Cell Signaling Studies: Utilized to investigate the role of sphingomyelin and its metabolites in apoptosis, proliferation, and stress responses.
• Cosmetic Science: Incorporated in high-end skincare formulations for its biomimetic properties, helping to restore and protect the skin's natural lipid barrier.

Basic Information

Product Name	n-Palmitoyl-D-Sphingomyelin
CAS No.	6254-89-3
Molecular Formula	C39H79N2O6P
Molecular Weight	703.03 g/mol
Synonyms	N-(Hexadecanoyl)-sphing-4-enine-1-phosphocholine; D-erythro-Sphingosine, 1-phosphocholine, N-palmitoyl-; Palmitoyl Sphingomyelin; SM(d18:1/16:0); N-Palmitoylsphingosylphosphorylcholine; Sphingomyelin (d18:1/16:0); LIPID MAPS ID: LMSP03010001
EINECS	Contact for details

Quality Control

Our n-Palmitoyl-D-Sphingomyelin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via mass spectrometry and NMR. Certificates of Analysis (COA) detailing batch-specific results are provided to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. The product is hygroscopic (moisture-sensitive). For long-term storage, keep under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Solubility	Soluble in chloroform/methanol mixtures, slightly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.