Description

Pyrazine-2,3-Dicarboxylic Acid Dimethyl Ester is a versatile heterocyclic building block and key synthetic intermediate prized for its rigid, planar structure and dual ester functionality. This compound is essential for the development of advanced materials and active pharmaceutical ingredients (APIs), enabling precise molecular design. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in ligand synthesis, polymer chemistry, and the creation of novel heterocyclic systems.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, particularly those containing pyrazine or diazine cores for antiviral, anticancer, or antimicrobial applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the pyrazine ring contributes to biological activity.
• Ligand and Chelating Agent: Serves as a starting material for the preparation of bidentate or polydentate ligands used in catalysis and metal-organic frameworks (MOFs).
• Polymer and Material Science: Acts as a monomer or cross-linking agent for producing high-performance polymers, dyes, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new heterocyclic chemistry, reaction pathways, and as a standard for analytical purposes.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing specific pyrazine-based aroma compounds, given the importance of alkylpyrazines in flavor chemistry.

Basic Information

Product Name	Pyrazine-2,3-Dicarboxylic Acid Dimethyl Ester
CAS No.	6164-77-8
Molecular Formula	C8H8N2O4
Molecular Weight	196.16 g/mol
Synonyms	Dimethyl Pyrazine-2,3-dicarboxylate; 2,3-Pyrazinedicarboxylic Acid Dimethyl Ester; Dimethyl 2,3-Pyrazinedicarboxylate; Pyrazine-2,3-dicarboxylic Acid Methyl Ester; Methyl Pyrazine-2,3-dicarboxylate; 2,3-Dimethoxycarbonylpyrazine; 6164-77-8; EINECS 228-213-7
EINECS	228-213-7

Quality Control

Our Pyrazine-2,3-Dicarboxylic Acid Dimethyl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.