Description

(9Z,15Z,R)-12-Hydroxy-9,15-Octadecadienoic Acid Methyl Ester is a high-purity, chiral hydroxy fatty acid methyl ester of significant interest in advanced organic synthesis and biochemical research. This compound matters as a key chiral intermediate and reference standard for studying lipid metabolism, enzyme activity, and the synthesis of bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of prostaglandin analogs, leukotriene derivatives, and other bioactive lipid mediators.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, particularly for lipoxygenases and other enzymes involved in fatty acid metabolism.
• Reference Standard: Employed as a high-purity analytical standard in HPLC, GC, and LC-MS methods for quality control and metabolic profiling.
• Agrochemical Synthesis: Acts as a precursor for developing novel plant growth regulators or environmentally benign pest control agents.
• Fine Chemical Production: Utilized in the manufacture of specialty surfactants, lubricants, and polymers where specific stereochemistry imparts desired functional properties.

Basic Information

Product Name	(9Z,15Z,R)-12-Hydroxy-9,15-Octadecadienoic Acid Methyl Ester
CAS No.	6114-36-9
Molecular Formula	C₁₉H₃₄O₃
Molecular Weight	310.47 g/mol
Synonyms	Methyl (R)-12-Hydroxy-9Z,15Z-octadecadienoate; Methyl (9Z,15Z,R)-12-Hydroxyoctadeca-9,15-dienoate; (R)-12-Hydroxy-9,15-octadecadienoic acid methyl ester; 12(R)-HODE Methyl Ester; 12(R)-HODE-ME; Methyl 12(R)-HODE; 12-Hydroxy-cis-9,cis-15-octadecadienoic Acid Methyl Ester (R-isomer)
EINECS	Contact for details

Quality Control

Our (9Z,15Z,R)-12-Hydroxy-9,15-Octadecadienoic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity and GC/HPLC for chemical purity, to ensure it meets the stringent requirements for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C under an inert atmosphere (e.g., argon or nitrogen) due to its sensitivity to oxidation. Allow the container to reach room temperature before opening to prevent moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% (R-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.