Description

(10E,12E,R)-9-Hydroxy-10,12-Octadecadienoic Acid Methyl Ester is a high-purity, stereochemically defined conjugated linoleic acid (CLA) derivative. This compound serves as a critical advanced intermediate and reference standard for research and development in life sciences and specialty chemistry. It is essential for organizations focused on lipid biochemistry, nutraceutical development, and pharmaceutical synthesis, where precise molecular structure and purity are paramount for reliable results.

Application

• Biochemical Research: Used as a key intermediate and reference standard in studies of lipid metabolism, peroxisome proliferator-activated receptor (PPAR) activity, and conjugated fatty acid pathways.
• Pharmaceutical Development: Serves as a building block or active pharmaceutical ingredient (API) intermediate for compounds targeting metabolic disorders and inflammation.
• Nutraceutical & Functional Food R&D: A vital component in the development of specialized conjugated linoleic acid (CLA) formulations aimed at weight management and metabolic health.
• Analytical Standard: Employed as a certified reference material (CRM) for the calibration of analytical instruments (HPLC, GC-MS) to ensure accurate quantification of CLA isomers in complex matrices.
• Cosmeceutical Ingredients: Investigated for use in advanced skincare formulations due to its potential bioactive properties.
• Organic Synthesis: Acts as a chiral synthon for the synthesis of more complex, stereospecific lipid molecules and prostaglandin analogs.

Basic Information

Product Name	(10E,12E,R)-9-Hydroxy-10,12-Octadecadienoic Acid Methyl Ester
CAS No.	6114-34-7
Molecular Formula	C₁₉H₃₄O₃
Molecular Weight	310.47 g/mol
Synonyms	Methyl (10E,12E,R)-9-Hydroxy-10,12-octadecadienoate; (R)-9-Hydroxy-10E,12E-octadecadienoic Acid Methyl Ester; 9-Hydroxy-10,12-octadecadienoic Acid Methyl Ester (10E,12E,R)-; CLA Methyl Ester Derivative; Methyl 9-Hydroxy-10,12-octadecadienoate; 9-Hydroxy-CLA Methyl Ester; (10E,12E)-9-Hydroxyoctadeca-10,12-dienoic Acid Methyl Ester (R-isomer)
EINECS	Contact for details

Quality Control

Our production of (10E,12E,R)-9-Hydroxy-10,12-Octadecadienoic Acid Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR to confirm identity, isomeric purity, and chemical potency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific research or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Isomeric Purity (GC/HPLC)	≥ 98.0% (10E,12E,R)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.